Why Tau PET Scans May Miss Alzheimer’s in Some Populations

Link: ScienceDaily – Tau PET threshold works in some groups but not Black adults

What the Study Did: A team from Washington University in St. Louis analyzed tau-PET scans using the 18F‑PI‑2620 tracer in a diverse sample. They found a diagnostic threshold that predicted impairment in Hispanic and White participants—but not in Black individuals.

Summary: This shows tau pathology may not explain cognitive decline equally across all groups.

Why It Matters: Diagnostic imaging may overlook Alzheimer’s in certain populations unless more inclusive criteria are developed.

Patient Takeaway: We use comprehensive, personalized evaluations that don’t rely solely on imaging—to serve all patients equitably.